Hematopoietic stem cell gene therapy: The optimal use of lentivirus and gene editing approaches
Abstract
Due to pioneering in vitro investigations on gene modification, gene engineering platforms have incredibly improved to a safer and more powerful tool for the treatment of multiple blood and immune disorders. Likewise, several clinical trials have been initiated combining autologous hematopoietic stem cell transplantation (auto-HSCT) with gene therapy (GT) tools. As several GT modalities such as lentivirus and gene editing tools have a long...
Paper Details
Title
Hematopoietic stem cell gene therapy: The optimal use of lentivirus and gene editing approaches
Published Date
Mar 1, 2020
Journal
Volume
40
Pages
100641 - 100641
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