Modified release of furosemide from Eudragits^® and poly(ethylene oxide)-based matrices and dry-coated tablets

Modified release of furosemide from tablet formulations is preferred by patients, because of physiological problems, acute diuresis being the most serious, compared to the forms designed for immediate release. With this in view, we aimed at achieving furosemide’s longer gastric retention and waste minimization by preparing matrix and compression coated tablets incorporating different grades of Eudragit ® and poly(ethylene oxide) (PEO),...