Original paper
Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress
Volume: 1866, Issue: 3, Pages: 165588 - 165588
Published: Mar 1, 2020
Abstract
The cytoplasmic peptide:N-glycanase (Ngly1) is a de-N-glycosylating enzyme that cleaves N-glycans from misfolded glycoproteins and is involved in endoplasmic reticulum-associated degradation. The recent discovery of NGLY1-deficiency, which causes severe systemic symptoms, drew attention to the physiological function of Ngly1 in mammals. While several studies have been carried out to reveal the physiological necessity of Ngly1, the semi-lethal...
Paper Details
Title
Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress
Published Date
Mar 1, 2020
Volume
1866
Issue
3
Pages
165588 - 165588
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Notes
History