Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function

Volume: 13, Issue: 6, Pages: 960 - 969
Published: Dec 1, 2019
Abstract
•Microgravity exposure resulted in changes in hiPSC-CM calcium-handling properties•2,635 genes were differentially expressed among flight, post-flight, and ground•Pathways related to mitochondrial function were enriched in space-flown hiPSC-CMs With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced...
Paper Details
Title
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function
Published Date
Dec 1, 2019
Journal
Volume
13
Issue
6
Pages
960 - 969
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