The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research

Volume: 15, Issue: 5, Pages: e0233057 - e0233057
Published: May 12, 2020
Abstract
Poor survival of human pluripotent stem cells (hPSCs) following freezing, thawing, or passaging hinders the maintenance and differentiation of stem cells. Rho-associated kinases (ROCKs) play a crucial role in hPSC survival. To date, a typical ROCK inhibitor, Y-27632, has been the primary agent used in hPSC research. Here, we report that another ROCK inhibitor, fasudil, can be used as an alternative and is cheaper than Y-27632. It increased hPSC...
Paper Details
Title
The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research
Published Date
May 12, 2020
Journal
Volume
15
Issue
5
Pages
e0233057 - e0233057
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