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Impact of 3-year changes in fasting insulin and insulin resistance indices on incident hypertension: Tehran lipid and glucose study.

Published on Jan 1, 2019in Nutrition & Metabolism3.599
· DOI :10.1186/S12986-019-0402-3
Aidin Baghbani-Oskouei2
Estimated H-index: 2
(Shahid Beheshti University of Medical Sciences and Health Services),
Maryam Tohidi22
Estimated H-index: 22
(Shahid Beheshti University of Medical Sciences and Health Services)
+ 2 AuthorsFarzad Hadaegh33
Estimated H-index: 33
(Shahid Beheshti University of Medical Sciences and Health Services)
Abstract
Background To examine the association between changes in fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), and insulin-glucose ratio (IGR) levels, over approximately 3 years with incident hypertension.
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References37
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Author(s): Arnett, Donna K; Blumenthal, Roger S; Albert, Michelle A; Buroker, Andrew B; Goldberger, Zachary D; Hahn, Ellen J; Himmelfarb, Cheryl D; Khera, Amit; Lloyd-Jones, Donald; McEvoy, J William; Michos, Erin D; Miedema, Michael D; Munoz, Daniel; Smith, Sidney C; Virani, Salim S; Williams, Kim A; Yeboah, Joseph; Ziaeian, Boback
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Abstract Background Studies on the association of fasting insulin concentrations or insulin resistance with subsequent risk of hypertension have yielded conflicting results. Objective To quantitatively assess the association of fasting insulin concentrations or homeostasis model assessment insulin resistance (HOMA-IR) with incident hypertension in a general population by performing a meta-analysis. Methods We searched the PubMed and Embase databases until August 31, 2016 for prospective observat...
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Background: Insulin resistance is a precursor of numerous chronic diseases, including cardiovascular disease (CVD). The fasting insulin concentration is considered a reasonable surrogate of insulin resistance, especially among nondiabetic individuals. Objective: We aimed to quantitatively summarize the literature on the association of fasting insulin concentrations with risk of hypertension, stroke, and coronary heart disease (CHD) by conducting a meta-analysis of prospective cohort studies. Des...
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