Signal: The home page of mutational signatures
Abstract
Background null The somatic mutations found through sequencing a whole tumour genome are the aggregate outcome of one or multiple mutational processes. Each of these processes leaves a characteristic imprint, or mutational signature, on the genome. The final mutational profile is determined by the pattern of exposure of each of these mutational processes. Deconstructing the signature composition of a tumour’s mutational profile provides insights...
Paper Details
Title
Signal: The home page of mutational signatures
Published Date
Nov 1, 2019
Journal
Volume
30
Pages
vii33 - vii33
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Notes
History