Separation, purification, structural analysis and immune-enhancing activity of sulfated polysaccharide isolated from sea cucumber viscera

A novel sulfated polysaccharide (SCVP-1) was isolated from sea cucumber viscera and purified to elucidate its structure and immune-enhancing ability. SCVP-1 was found to be a homogeneous polysaccharide with a relative molecular weight of 180.8 kDa and composed of total sugars (60.2 ± 2.6%), uronic acid (15.3 ± 1.8%), proteins (6.8 ± 0.8%), and sulfate groups (18.1 ± 0.9%). SCVP-1 consisted of mannose, glucosamine, glucuronic acid,...