Antidepressant effects of ketamine on depression-related phenotypes and dopamine dysfunction in rodent models of stress

Volume: 379, Pages: 112367 - 112367
Published: Feb 1, 2020
Abstract
Depression, the most prevalent psychiatric disorder, is characterized by increased negative affect (i.e. depressed mood) and reduced positive affect (i.e. anhedonia). Stress is a risk factor for depression in humans, and animal models of chronic stress are typically used to study neurobehavioral alterations relevant to depression. Common behavioral outcomes in rodent models of chronic stress include anhedonia, social dysfunction and behavioral...
Paper Details
Title
Antidepressant effects of ketamine on depression-related phenotypes and dopamine dysfunction in rodent models of stress
Published Date
Feb 1, 2020
Volume
379
Pages
112367 - 112367
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