Perspectives on the Changing Landscape of Measuring Cardiovascular Risk Related to LDL

The clinical laboratory plays a critical role in the assessment of atherosclerotic cardiovascular disease (ASCVD)9 risk. Since the 1970s, this laboratory assessment has been primarily through tests in the lipid panel, which included cholesterol, triglycerides (TG), and HDL cholesterol (HDL-C) based on fasting serum or plasma specimens. Until the advent of direct LDL cholesterol (LDL-C) tests approximately 20 years ago, LDL-C was almost...