Derlin‐1 exhibits oncogenic activities and indicates an unfavorable prognosis in breast cancer
Abstract
Derlin-1 is involved in the elimination of misfolded proteins and has been implicated in the progression of human cancers. However, its prognostic value and biological function in breast cancer remain unknown. Here, we show that Derlin-1 is overexpressed in breast cancer and exhibits oncogenic activities via interaction with UBE2C. Increased expression of Derlin-1 is correlated with lymph node metastasis, advanced clinical stage, and unfavorable...
Paper Details
Title
Derlin‐1 exhibits oncogenic activities and indicates an unfavorable prognosis in breast cancer
Published Date
Nov 26, 2019
Journal
Volume
44
Issue
2
Pages
593 - 602
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