Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation.

Volume: 20, Issue: 4, Pages: 1125 - 1136
Published: Feb 3, 2020
Abstract
Regulatory T cells (Tregs) are a lymphocyte subset with intrinsic immunosuppressive properties that can be expanded in large numbers ex vivo and have been shown to prevent allograft rejection and promote tolerance in animal models. To investigate the safety, applicability, and biological activity of autologous Treg adoptive transfer in humans, we conducted an open-label, dose-escalation, Phase I clinical trial in liver transplantation. Patients...
Paper Details
Title
Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation.
Published Date
Feb 3, 2020
Volume
20
Issue
4
Pages
1125 - 1136
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