Evaluation of Sperm Impairing Factor from Serratia marcescens as Male Contraceptive in Mouse Model

The present study was carried out to assess the contraceptive efficacy of sperm agglutinating factor (SAF) isolated from Serratia marcescens , in male Balb/c mice. Mice were administered via an intratesticular route with different concentrations of SAF, viz. , 10, 50, 100, 200, or 400 µ g, in the right testis only which served as a test while the left side served as control except otherwise stated. Mice were sacrificed on day 3, 7, 14, 21, 30,...