Ferulic acid reinstates mitochondrial dynamics through PGC1α expression modulation in 6‐hydroxydopamine lesioned rats

Volume: 34, Issue: 1, Pages: 214 - 226
Published: Oct 27, 2019
Abstract
Disruption of the tightly regulated mitochondrial dynamics and energy homeostasis leads to oxidative stress and apoptotic cell death, as observed in neurodegenerative disorders such as Parkinson's disease (PD). Polyphenolic plant derivatives have been shown to alleviate such pathological features and have been used in models of neurodegenerative disorders in previous reports. In the current study, we utilized a 6‐hydroxydopamine (6‐OHDA)...
Paper Details
Title
Ferulic acid reinstates mitochondrial dynamics through PGC1α expression modulation in 6‐hydroxydopamine lesioned rats
Published Date
Oct 27, 2019
Volume
34
Issue
1
Pages
214 - 226
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