Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus
Abstract
P53 and its family member p63 play important roles in cellular senescence and organismal aging. In this study, p53 and p63 immunoreactivity were examined in the hippocampus of young, adult and aged mice by using immunohistochemistry. In addition, neuronal distribution and degeneration was examined by NeuN immunohistochemistry and fluoro-Jade B fluorescence staining. Strong p53 immunoreactivity was mainly expressed in pyramidal and granule cells...
Paper Details
Title
Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus
Published Date
Oct 29, 2019
Journal
Volume
35
Issue
1
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