The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS
Volume: 201, Issue: 5, Pages: 540 - 554
Published: Mar 1, 2020
Abstract
Rationale: The role of PI (protease inhibitor) type Z heterozygotes and additional rare variant genotypes in the gene encoding alpha-1 antitrypsin, SERPINA1 (serpin peptidase inhibitor, clade A, member 1), in determining chronic obstructive pulmonary disease risk and severity is controversial.Objectives: To comprehensively evaluate the effects of rare SERPINA1 variants on lung function and emphysema phenotypes in subjects with significant...
Paper Details
Title
The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS
Published Date
Mar 1, 2020
Volume
201
Issue
5
Pages
540 - 554
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