P1.09-24 Tumor Necrosis Correlates with PD-L1 and PD-1 Expression in Lung Adenocarcinoma

Predictive biomarkers for immunotherapy in lung cancer are intensively investigated, however, correlations between PD-L1/PD-1 expressions and clinical features or histopathological tumor characteristics determined on hematoxylin and eosin stained sections have not extensively been studied. We determined PD-L1 expression of tumor cells (TC) and immune cells (IC), and PD-1 expression of IC by immunohistochemistry in 268 lung adenocarcinoma (LADC)...