P4667Loss of function in PCSK9, atherogenic lipoprotein concentrations, and calcific aortic valve stenosis
Abstract
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition reduces plasma concentrations of most atherogenic lipoproteins such as low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB) and lipoprotein(a) [Lp(a)]. Atherogenic lipoprotein concentrations have also been linked with calcific aortic valve stenosis (CAVS). Purpose 1) To determine the association between genetic variants in PCSK9 and lipoprotein-lipid...
Paper Details
Title
P4667Loss of function in PCSK9, atherogenic lipoprotein concentrations, and calcific aortic valve stenosis
Published Date
Oct 1, 2019
Journal
Volume
40
Issue
Supplement_1
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