Antiproliferative evaluation of various aminoquinoline derivatives

Volume: 69, Issue: 4, Pages: 661 - 672
Published: Dec 1, 2019
Abstract
Four classes of aminoquinoline derivatives were prepared: primaquine ureas 1a–f, primaquine bis-ureas 2a–f, chloroquine fumardiamides 3a–f and mefloquine fumardiamides 4a–f. Their antiproliferative activities against breast adenocarcinoma (MCF-7), lung carcinoma (H460) and colon carcinoma (HCT 116 and SW620) cell lines were evaluated in vitro, using MTT cell proliferation assay. The results revealed a low activity of primaquine urea and bis-urea...
Paper Details
Title
Antiproliferative evaluation of various aminoquinoline derivatives
Published Date
Dec 1, 2019
Volume
69
Issue
4
Pages
661 - 672
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