ZNF774 is a potent suppressor of hepatocarcinogenesis through dampening the NOTCH2 signaling
Abstract
Discerning oncogenic drivers from passengers remain a major effort in understanding of the essence of the initiation and development of hepatocellular carcinoma (HCC), which is the most common primary liver malignancy and the third leading cause of cancer mortality worldwide. Here we report that ZNF774, a novel zinc-finger protein, inhibits the proliferation and invasion of HCC cells. Molecular characterization of this protein indicated that...
Paper Details
Title
ZNF774 is a potent suppressor of hepatocarcinogenesis through dampening the NOTCH2 signaling
Published Date
Oct 28, 2019
Journal
Volume
39
Issue
8
Pages
1665 - 1680
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Notes
History