P2.12-02 Intertumoral Heterogeneity in Small Cell Lung Carcinoma According to the Primary Tumor Versus Lymph Node Metastases Delineated by RNA Sequencing

The pathological diagnosis of small cell lung cancer (SCLC) was determined mainly based on the simple morphological pattern for decades with no significant therapeutic advancements. Exploring the gene expression profile of matched primary and lymph node (LN) metastatic SCLC tumors might provide unique insights into new potential therapeutic approaches. A total of 32 histologically confirmed SCLC patients underwent surgical resection with...