High uric acid, reduced glomerular filtration rate and non-alcoholic fatty liver in young people with obesity

To evaluate the association between high uric acid (UA), reduced estimated glomerular filtration rate (eGFR), and non-alcoholic fatty liver disease (NAFLD) in outpatient children and adolescents with overweight (OW) or obesity (OB). Anthropometric, biochemical, hepatic ultrasound and eGFR data were available from 2565 young people with OW/OB (age 5–18 years). eGFR was calculated using the Schwartz’s bedside formula and reduced eGFR (ReGFR+) was...