Preparation and evaluation of spray dried rosuvastatin calcium-PVP microparticles for the improvement of serum lipid profile

Volume: 55, Pages: 101342 - 101342
Published: Feb 1, 2020
Abstract
The poor physicochemical properties of rosuvastatin calcium (ROS) remains a challenge for dosage form development. In the present study, we explore the development of spray dried ROS loaded PVP microparticles to improve the release of ROS as well as the anti-hyperlipidemic efficacy. The ROS loaded PVP microparticles (F1–F3) were developed by spray drying method with a range of particle size (1.26–1.67 μm), PDI (0.138-0.267), PDE (78 ± 3.2 to...
Paper Details
Title
Preparation and evaluation of spray dried rosuvastatin calcium-PVP microparticles for the improvement of serum lipid profile
Published Date
Feb 1, 2020
Volume
55
Pages
101342 - 101342
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