P2.04-25 Gut Mycobiome and Metabolic Interactions with Bacteria in Lung Cancer Patients Reveals Potential Therapeutic Vulnerabilities

There is a lack in our understanding of pathogenesis and mechanisms accounting for large variability in response to systemic therapy. Recent data suggest that the gut-lung axis regulates systemic immune function. Moreover, in vivo and clinical studies, mainly in melanoma and mixed epithelial tumors, suggest the role of gut bacteria and response to systemic therapy. However, the presence and potential theranostic role of gastrointestinal (GI)...