RelZ-Mediated Stress Response in Mycobacterium smegmatis : pGpp Synthesis and Its Regulation
Abstract
Bacteria utilize nucleotide messengers to survive the hostile environmental conditions and the onslaught of attacks within the host. The second messengers guanosine tetraphosphate and pentaphosphate [(p)ppGpp] have a profound impact on the long-term survival, biofilm formation, antibiotic tolerance, virulence, and pathogenesis of bacteria. Therefore, understanding the stress response mechanism regulated by (p)ppGpp is essential for discovering...
Paper Details
Title
RelZ-Mediated Stress Response in Mycobacterium smegmatis : pGpp Synthesis and Its Regulation
Published Date
Jan 2, 2020
Journal
Volume
202
Issue
2
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