Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450
Abstract
Biological effects of flavonoids have been extensively studied in the last 80 years. As flavonoids represent a rather large group of compounds, data on metabolic biotransformations of these compounds is relatively limited to those well studied. The objective of this study was to screen the metabolism of 30 selected flavonoid aglycons mediated by the most relevant metabolic enzymes, human liver cytochromes P450. For this purpose, in vitro...
Paper Details
Title
Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450
Published Date
Oct 21, 2019
Journal
Volume
69
Issue
4
Pages
541 - 562
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