Imatinib and the long tail of targeted drug development
Abstract
New molecular insights occasionally lead to the rapid development of therapeutic agents that improve the outcomes of patients with cancer; however, these breakthroughs can be followed by extensive, empirically driven and often unsuccessful efforts at extending the drug to other indications or combinations. Herein, we describe the clinical development of imatinib, a paradigm of rapid molecularly driven drug development, and advocate for a...
Paper Details
Title
Imatinib and the long tail of targeted drug development
Published Date
Oct 24, 2019
Volume
17
Issue
1
Pages
1 - 3
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