Plasma Clusterin as a Potential Biomarker for Alzheimer’s Disease-A Systematic Review and Meta-analysis

Background: Plasma clusterin has been reported to be associated with the pathology, prevalence, severity, and rapid clinical progress of Alzheimer’s Disease (AD). However, whether plasma clusterin can be used as a biomarker of AD is inconsistent and even conflicting. Objective: We conducted this study to evaluate the potential of plasma clusterin as the biomarker of AD. Method: PubMed, Embase, and Cochrane databases were systematically searched...