Effective Connectivity Between Broca’s Area and Amygdala as a Mechanism of Top-Down Control in Worry

Individuals higher in trait worry exhibit increased activation in Broca’s area during inhibitory processing tasks. To identify whether such activity represents an adaptive mechanism supporting top-down control, we investigated functional and effective connectivity of Broca’s area during a task of inhibitory control. Functional MRI data obtained from 106 participants performing an emotion-word Stroop task were examined using psychophysiological...