A Model of Indirect Cell Death Caused by Tumor Vascular Damage after High-Dose Radiotherapy
Abstract
There is increasing evidence that high doses of radiotherapy, like those delivered in stereotactic body radiotherapy (SBRT), trigger indirect mechanisms of cell death. Such effect seems to be two-fold. High doses may trigger an immune response and may cause vascular damage, leading to cell starvation and death. Development of mathematical response models, including indirect death, may help clinicians to design SBRT optimal schedules. Despite...
Paper Details
Title
A Model of Indirect Cell Death Caused by Tumor Vascular Damage after High-Dose Radiotherapy
Published Date
Dec 1, 2019
Journal
Volume
79
Issue
23
Pages
6044 - 6053
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