Mycobacterium tuberculosis programs mesenchymal stem cells to establish dormancy and persistence

Volume: 130, Issue: 2, Pages: 655 - 661
Published: Dec 17, 2019
Abstract
Tuberculosis (TB) remains a major infectious disease worldwide. TB treatment displays a biphasic bacterial clearance, in which the majority of bacteria clear within the first month of treatment, but residual bacteria remain nonresponsive to treatment and eventually may become resistant. Here, we have shown that Mycobacterium tuberculosis was taken up by mesenchymal stem cells (MSCs), where it established dormancy and became highly nonresponsive...
Paper Details
Title
Mycobacterium tuberculosis programs mesenchymal stem cells to establish dormancy and persistence
Published Date
Dec 17, 2019
Volume
130
Issue
2
Pages
655 - 661
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