Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank

Clinical and epidemiologic studies have shown that obesity is associated with asthma and that these associations differ by asthma subtype. Little is known about the shared genetic components between obesity and asthma.We sought to identify shared genetic associations between obesity-related traits and asthma subtypes in adults.A cross-trait genome-wide association study (GWAS) was performed using 457,822 subjects of European ancestry from the UK...