Taxumarienes A–G, seven new α-glucosidase inhibitory taxane-diterpenoids from the leaves of Taxus mairei

Seven new taxane diterpenoids taxumarienes A–G (1–7) were isolated from the leaves of Taxus mairei, along with seven known analogous (8–14). The structures of the new compounds were elucidated based on the analysis of NMR and MS spectroscopy. All isolates were evaluated for their α-glucosidase inhibitory activities. Among them, taxumarienes A (1) and F (6) showed potent effect with IC50 values of 5.9 ± 1.30 μM and 3.7 ± 0.75 μM,...