Programmed Cell Death inNeurospora crassaIs Controlled by the Allorecognition Determinantrcd-1

Programmed cell death preventing heterokaryon formation in fungi has been proposed to represent a defense mechanism against conspecific genome exploitation and mycoviruses. Here, Daskalov et al. identified a novel genetic determinant of allorecognition... Nonself recognition following cell fusion between genetically distinct individuals of the same species in filamentous fungi often results in a programmed cell death (PCD) reaction, where the...