Modelling multilevel spatial behaviour in binary-mark muscle fibre configurations

The functional properties of skeletal muscles depend on the spatial arrangements of fast and slow muscle fibre types. Qualitative assessment of muscle configurations suggest that muscle disease and normal ageing are associated with visible changes in the spatial pattern, though a lack of statistical modelling hinders our ability to formally assess such trends. We design a nested Gaussian conditional autoregressive (CAR) model to quantify spatial...