Genomic integrity of human induced pluripotent stem cells: Reprogramming, differentiation and applications

Volume: 11, Issue: 10, Pages: 729 - 747
Published: Oct 26, 2019
Abstract
Ten years after the initial generation of induced pluripotent stem cells (hiPSCs) from human tissues, their potential is no longer questioned, with over 15000 publications listed on PubMed, covering various fields of research; including disease modeling, cell therapy strategies, pharmacology/toxicology screening and 3D organoid systems. However, despite evidences that the presence of mutations in hiPSCs should be a concern, publications...
Paper Details
Title
Genomic integrity of human induced pluripotent stem cells: Reprogramming, differentiation and applications
Published Date
Oct 26, 2019
Volume
11
Issue
10
Pages
729 - 747
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