Non‐enzymatic reaction of carnosine and glyceraldehyde‐3‐phosphate accompanies metabolic changes of the pentose phosphate pathway
Abstract
Objectives Carnosine (β-alanyl-l-histidine) is a naturally occurring dipeptide that selectively inhibits cancer cell growth, possibly by influencing glucose metabolism. As its precise mode of action and its primary targets are unknown, we analysed carnosine's effect on metabolites and pathways in glioblastoma cells. Materials and methods Glioblastoma cells, U87, T98G and LN229, were treated with carnosine, and metabolites were analysed by gas...
Paper Details
Title
Non‐enzymatic reaction of carnosine and glyceraldehyde‐3‐phosphate accompanies metabolic changes of the pentose phosphate pathway
Published Date
Oct 19, 2019
Journal
Volume
53
Issue
2
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