Discovery, Functional Characterization and Therapeutic Targeting of Lnc-17-92 Metabolic Signaling in Multiple Myeloma

Long noncoding RNAs (lncRNAs) play key roles in regulating chromatin dynamics and gene expression. We have recently described the lncRNA landscape in multiple myeloma (MM) and reported their role as independent risk predictors for clinical outcome, providing a strong rationale to evaluate their molecular and biological impact in the disease. From this lncRNA profile, we have identified lnc-17-92 as an independent risk predictor highly...