Reduced cortical somatostatin gene expression in a rat model of maternal immune activation
Abstract
Alterations in GABAergic interneurons and glutamic acid decarboxylase (GAD) are observed in the brains of people with schizophrenia. Studies also show increased density of interstitial white matter neurons (IWMN), including those containing GAD and somatostatin (SST) in the brain in schizophrenia. Maternal immune activation can be modelled in rodents to investigate the relationship between prenatal exposure to infections and increased risk of...
Paper Details
Title
Reduced cortical somatostatin gene expression in a rat model of maternal immune activation
Published Date
Dec 1, 2019
Journal
Volume
282
Pages
112621 - 112621
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History