Exploiting plant cell culture for natural product formation

The initiation of callus cultures and in vitro cultivation of plant cells, even in large bioreactors, has become a routine task. Despite the fact, that permanent cell and organ cultures can produce a whole range of small natural compounds (SNAPs) used in medicine, only a few could be produced at commercial scale. However, plant cell cultures provide very useful systems to study the biosynthetic pathways leading to SNAPs at the enzyme and gene...