P1‐029: CHANGE IN BLOOD PRESSURE AND THE RISK OF DEMENTIA OVER 26 YEARS: THE ROTTERDAM STUDY

The controversial role of the direction of change, i.e. a rise or fall in blood pressure (BP), has been the focus of the long-lasting debate in the relation between change of BP and dementia. Insufficient attention has been given to the role of the magnitude, i.e. a small or large change in BP. We hypothesized that the magnitude of change in BP matters more than the direction in the association with incident dementia. In a prospective cohort...