O2-07-02: SLEEP QUALITY BUT NOT SLEEP QUANTITY IS ASSOCIATED WITH ALTERED BRAIN ACTIVATION DURING ENCODING IN POSTMENOPAUSAL WOMEN

Sleep quality is a key determinant of brain aging. For example, disturbed sleep, assessed with actigraphy-based measures of sleep efficiency, has been associated with amyloid deposition and cognitive dysfunction in cognitively normal older adults. These associations were stronger than associations with sleep quantity (e.g., total sleep time). Here we examined actigraphy-based measures of sleep efficiency versus total sleep time in relation to...