Schisantherin A induces cell apoptosis through ROS/JNK signaling pathway in human gastric cancer cells
Abstract
Gastric cancer is one of the most lethal cancers with unmet clinical treatment and low 5-year survival rate. Schisantherin A is a major compound derived from Fructusschisandrae while its anti-tumor role remains nearly unknown. Here, we reported that schisantherin A had an anti-proliferation effect on gastric cancer cell lines MKN45 and SGC-7901. Schisantherin A induced cell cycle arrest at G2/M phase and cell apoptosis, and inhibited cell...
Paper Details
Title
Schisantherin A induces cell apoptosis through ROS/JNK signaling pathway in human gastric cancer cells
Published Date
Mar 1, 2020
Journal
Volume
173
Pages
113673 - 113673
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