How Boundaries Form: Linked Nonautonomous Feedback Loops Regulate Pattern Formation in Yeast Colonies

How do boundaries between cells of different types form? Such boundaries are critical for metazoan development, but even in microorganisms, boundaries between cells of different types form in communities such as colonies... Under conditions in which budding yeast form colonies and then undergo meiosis/sporulation, the resulting colonies are organized such that a sharply defined layer of meiotic cells overlays a layer of unsporulated cells termed...