Reliability of Protein Abundance and Synthesis Measurements in Human Skeletal Muscle
Abstract
We investigated the repeatability of dynamic proteome profiling (DPP), which is a novel technique for measuring the relative abundance (ABD) and fractional synthesis rate (FSR) of proteins in humans. LC-MS analysis was performed on muscle samples taken from male participants (n = 4) that consumed 4 × 50 ml doses of deuterium oxide (2 H2 O) per day for 14 d. ABD was measured by label-free quantitation and FSR was calculated from time-dependent...
Paper Details
Title
Reliability of Protein Abundance and Synthesis Measurements in Human Skeletal Muscle
Published Date
Apr 1, 2020
Journal
Volume
20
Issue
7
Pages
1900194 - 1900194
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