hERG Function in Light of Structure
Abstract
The human ether-a-go-go-related gene1 (hERG) ion channel has been the subject of fascination since it was identified as a target of long QT syndrome more than 20 years ago. In this Biophysical Perspective, we look at what makes hERG intriguing and vexingly unique. By probing recent high-resolution structures in the context of functional and biochemical data, we attempt to summarize new insights into hERG-specific function and articulate...
Paper Details
Title
hERG Function in Light of Structure
Published Date
Feb 1, 2020
Journal
Volume
118
Issue
4
Pages
790 - 797
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History