The Relationship between Mutation in HOXB1 Gene and Acute Myeloid Leukemia
Abstract
Background: HOX genes are an exceedingly preserved family of homeodomain-involving transcription factors. They are related to a number of malignancies, comprising acute myeloid leukemia (AML). This study aimed to evaluate the effect of HOXB1 7bp deletion mutation on HOXB1gene expression in 36 individuals.
Materials and Methods: The present cross-sectional study was done on a large Iranian family. In this experimental study, 5 homozygous...
Paper Details
Title
The Relationship between Mutation in HOXB1 Gene and Acute Myeloid Leukemia
Published Date
Oct 14, 2019
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