A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies
Abstract
Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments. Autosomal dominant mutations in the MAPT gene cause heterogeneous forms of frontotemporal lobar degeneration with tauopathy (FTLD-Tau). Common and rare variants in the MAPT gene increase the risk for sporadic FTLD-Tau,...
Paper Details
Title
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies
Published Date
Nov 1, 2019
Journal
Volume
13
Issue
5
Pages
939 - 955
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