Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity
Abstract
Non-alcoholic fatty liver disease (NAFLD) represents a key feature of obesity-related type 2 diabetes with increasing prevalence worldwide. To our knowledge, no treatment options are available to date, paving the way for more severe liver damage, including cirrhosis and hepatocellular carcinoma. Here, we show an unexpected function for an intracellular trafficking regulator, the small Rab GTPase Rab24, in mitochondrial fission and activation,...
Paper Details
Title
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity
Published Date
Oct 14, 2019
Journal
Volume
1
Issue
10
Pages
1009 - 1026
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Notes
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