The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
Abstract
Chromosomal instability (CIN) is an intricate phenomenon that is often found in human cancer, characterized by persisting errors in chromosome segregation. This ongoing chromosome mis-segregation results in structural and numerical chromosomal abnormalities that have been widely described to promote tumor evolution. In addition to being a driver of tumor evolution, recent evidence demonstrates CIN to be the central node of the crosstalk between...
Paper Details
Title
The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
Published Date
Oct 10, 2019
Journal
Volume
8
Issue
10
Pages
1228 - 1228
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